Tania Dottorini

2024

Application of deep learning for livestock behaviour recognition: A systematic literature review

Rohan, A., Rafaq, M. S., Hasan, M. J., Asghar, F., Bashir, A. K. & Dottorini, T., Sept 2024, In: Computers and Electronics in Agriculture. 224, 109115.

Research output: Journal Publication › Review article › peer-review

Open Access

Convergence of resistance and evolutionary responses in Escherichia coli and Salmonella enterica co-inhabiting chicken farms in China

Baker, M., Zhang, X., Maciel-Guerra, A., Babaarslan, K., Dong, Y., Wang, W., Hu, Y., Renney, D., Liu, L., Li, H., Hossain, M., Heeb, S., Tong, Z., Pearcy, N., Zhang, M., Geng, Y., Zhao, L., Hao, Z., Senin, N. & Chen, J. & 3 others, Peng, Z., Li, F. & Dottorini, T., Dec 2024, In: Nature Communications. 15, 1, 206.

Research output: Journal Publication › Article › peer-review

Open Access

6 Citations (Scopus)

2023

Accurate prediction of calving in dairy cows by applying feature engineering and machine learning

Vázquez-Diosdado, J. A., Gruhier, J., Miguel-Pacheco, G. G., Green, M., Dottorini, T. & Kaler, J., Oct 2023, In: Preventive Veterinary Medicine. 219, 106007.

Research output: Journal Publication › Article › peer-review

2 Citations (Scopus)

Activated tissue resident memory T-cells (CD8+CD103+CD39+) uniquely predict survival in left sided “immune-hot” colorectal cancers

Talhouni, S., Fadhil, W., Mongan, N. P., Field, L., Hunter, K., Makhsous, S., Maciel-Guerra, A., Kaur, N., Nestarenkaite, A., Laurinavicius, A., Willcox, B. E., Dottorini, T., Spendlove, I., Jackson, A. M., Ilyas, M. & Ramage, J. M., 2023, In: Frontiers in Immunology. 14, 1057292.

Research output: Journal Publication › Article › peer-review

Open Access

6 Citations (Scopus)

Dissecting microbial communities and resistomes for interconnected humans, soil, and livestock

Maciel-Guerra, A., Baker, M., Hu, Y., Wang, W., Zhang, X., Rong, J., Zhang, Y., Zhang, J., Kaler, J., Renney, D., Loose, M., Emes, R. D., Liu, L., Chen, J., Peng, Z., Li, F. & Dottorini, T., Jan 2023, In: ISME Journal. 17, 1, p. 21-35 15 p.

Research output: Journal Publication › Article › peer-review

Open Access

25 Citations (Scopus)

Improving antimicrobial resistance surveillance in livestock production

Baker, M. & Dottorini, T., Aug 2023, In: Nature Food. 4, 8, p. 646-647 2 p.

Research output: Journal Publication › Comment/debate

Machine learning and metagenomics reveal shared antimicrobial resistance profiles across multiple chicken farms and abattoirs in China

Baker, M., Zhang, X., Maciel-Guerra, A., Dong, Y., Wang, W., Hu, Y., Renney, D., Hu, Y., Liu, L., Li, H., Tong, Z., Zhang, M., Geng, Y., Zhao, L., Hao, Z., Senin, N., Chen, J., Peng, Z., Li, F. & Dottorini, T., Aug 2023, In: Nature Food. 4, 8, p. 707-720 14 p.

Research output: Journal Publication › Article › peer-review

Open Access

14 Citations (Scopus)

Predicting bioactivity of antibiotic metabolites by molecular docking and dynamics

Chio, H., Guest, E. E., Hobman, J. L., Dottorini, T., Hirst, J. D. & Stekel, D. J., Sept 2023, In: Journal of Molecular Graphics and Modelling. 123, 108508.

Research output: Journal Publication › Article › peer-review

Open Access

3 Citations (Scopus)

2022

Identifying associations between management practices and antimicrobial resistances of sentinel bacteria recovered from bulk tank milk on dairy farms

McLaughlin, D., Bradley, A., Dottorini, T., Giebel, K., Leach, K., Hyde, R. & Green, M., Jul 2022, In: Preventive Veterinary Medicine. 204, 105666.

Research output: Journal Publication › Article › peer-review

Open Access

5 Citations (Scopus)

Novel SCCmec type XV (7A) and two pseudo-SCCmec variants in foodborne MRSA in China

Wang, W., Hu, Y., Baker, M., Dottorini, T., Li, H., Dong, Y., Bai, Y., Fanning, S. & Li, F., 1 Apr 2022, In: Journal of Antimicrobial Chemotherapy. 77, 4, p. 903-909 7 p.

Research output: Journal Publication › Article › peer-review

Open Access

17 Citations (Scopus)

Whole-genome sequencing and gene sharing network analysis powered by machine learning identifies antibiotic resistance sharing between animals, humans and environment in livestock farming

Peng, Z., Maciel-Guerra, A., Baker, M., Zhang, X., Hu, Y., Wang, W., Rong, J., Zhang, J., Xue, N., Barrow, P., Renney, D., Stekel, D., Williams, P., Liu, L., Chen, J., Li, F. & Dottorini, T., Mar 2022, In: PLoS Computational Biology. 18, 3, e1010018.

Research output: Journal Publication › Article › peer-review

Open Access

19 Citations (Scopus)

2021

A multi-factorial observational study on sequential fecal microbiota transplant in patients with medically refractory clostridioides difficile infection

Monaghan, T. M., Duggal, N. A., Rosati, E., Griffin, R., Hughes, J., Roach, B., Yang, D. Y., Wang, C., Wong, K., Saxinger, L., Pučić-Baković, M., Vučković, F., Klicek, F., Lauc, G., Tighe, P., Mullish, B. H., Blanco, J. M., McDonald, J. A. K., Marchesi, J. R. & Xue, N. & 12 others, Dottorini, T., Acharjee, A., Franke, A., Li, Y., Wong, G. K. S., Polytarchou, C., Yau, T. O., Christodoulou, N., Hatziapostolou, M., Wang, M., Russell, L. A. & Kao, D. H., Nov 2021, In: Cells. 10, 11, 3234.

Research output: Journal Publication › Article › peer-review

Open Access

12 Citations (Scopus)

Comparative Genomic Analysis of the Foodborne Pathogen Burkholderia gladioli pv. cocovenenans Harboring a Bongkrekic Acid Biosynthesis Gene Cluster

Peng, Z., Dottorini, T., Hu, Y., Li, M., Yan, S., Fanning, S., Baker, M., Xu, J. & Li, F., 17 May 2021, In: Frontiers in Microbiology. 12, 628538.

Research output: Journal Publication › Article › peer-review

Open Access

17 Citations (Scopus)

Genome-scale metabolic models and machine learning reveal genetic determinants of antibiotic resistance in escherichia coli and unravel the underlying metabolic adaptation mechanisms

Pearcy, N., Hu, Y., Baker, M., Maciel-Guerra, A., Xue, N., Wang, W., Kaler, J., Peng, Z., Li, F. & Dottorini, T., Jul 2021, In: mSystems. 6, 4, e00913-20.

Research output: Journal Publication › Article › peer-review

Open Access

27 Citations (Scopus)

Mass spectrometry and machine learning for the accurate diagnosis of benzylpenicillin and multidrug resistance of Staphylococcus aureus in bovine mastitis

Esener, N., Guerra, A. M., Giebel, K., Lea, D., Green, M. J., Bradley, A. J. & Dottorini, T., Jun 2021, In: PLoS Computational Biology. 17, 6, e1009108.

Research output: Journal Publication › Article › peer-review

Open Access

15 Citations (Scopus)

Multiomics profiling reveals signatures of dysmetabolism in urban populations in central India

Monaghan, T. M., Biswas, R. N., Nashine, R. R., Joshi, S. S., Mullish, B. H., Seekatz, A. M., Blanco, J. M., McDonald, J. A. K., Marchesi, J. R., Yau, T. O., Christodoulou, N., Hatziapostolou, M., Pucic‐bakovic, M., Vuckovic, F., Klicek, F., Lauc, G., Xue, N., Dottorini, T., Ambalkar, S. & Satav, A. & 3 others, Polytarchou, C., Acharjee, A. & Kashyap, R. S., Jul 2021, In: Microorganisms. 9, 7, 1485.

Research output: Journal Publication › Article › peer-review

Open Access

3 Citations (Scopus)

Prediction of Streptococcus uberis clinical mastitis treatment success in dairy herds by means of mass spectrometry and machine-learning

Maciel-Guerra, A., Esener, N., Giebel, K., Lea, D., Green, M. J., Bradley, A. J. & Dottorini, T., Dec 2021, In: Scientific Reports. 11, 1, 7736.

Research output: Journal Publication › Article › peer-review

Open Access

5 Citations (Scopus)

Transcriptomic Analysis of Cardiomyocyte Extracellular Vesicles in Hypertrophic Cardiomyopathy Reveals Differential snoRNA Cargo

James, V., Nizamudeen, Z. A., Lea, D., Dottorini, T., Holmes, T. L., Johnson, B. B., Arkill, K. P., Denning, C. & Smith, J. G. W., 15 Dec 2021, In: Stem Cells and Development. 30, 24, p. 1215-1227 13 p.

Research output: Journal Publication › Article › peer-review

Open Access

13 Citations (Scopus)

Ultra-conserved sequences in the genomes of highly diverse Anopheles mosquitoes, with implications for malaria vector control

O'Loughlin, S. M., Forster, A. J., Fuchs, S., Dottorini, T., Nolan, T., Crisanti, A. & Burt, A., Jun 2021, In: G3: Genes, Genomes, Genetics. 11, 6, jkab086.

Research output: Journal Publication › Article › peer-review

Open Access

3 Citations (Scopus)

Whole-genome sequencing and machine learning analysis of staphylococcus aureus from multiple heterogeneous sources in china reveals common genetic traits of antimicrobial resistance

Wang, W., Baker, M., Hu, Y., Xu, J., Yang, D., Maciel-Guerra, A., Xue, N., Li, H., Yan, S., Li, M., Bai, Y., Dong, Y., Peng, Z., Ma, J., Li, F. & Dottorini, T., Jun 2021, In: mSystems. 6, 3, e01185-20.

Research output: Journal Publication › Article › peer-review

Open Access

24 Citations (Scopus)

2020

Automated detection of lameness in sheep using machine learning approaches: Novel insights into behavioural differences among lame and non-lame sheep

Kaler, J., Mitsch, J., Vázquez-Diosdado, J. A., Bollard, N., Dottorini, T. & Ellis, K. A., 1 Jan 2020, In: Royal Society Open Science. 7, 1, 190824.

Research output: Journal Publication › Article › peer-review

Open Access

34 Citations (Scopus)

Epidemiological study on prevalence, serovar diversity, multidrug resistance, and CTX-M-type extended-spectrum β-lactamases of salmonella spp. From patients with diarrhea, food of animal origin, and pets in Several Provinces of China

Wang, W., Zhao, L., Hu, Y., Dottorini, T., Fanning, S., Fanning, S., Fanning, S., Xu, J. & Li, F., Jul 2020, In: Antimicrobial Agents and Chemotherapy. 64, 7, e00092-20.

Research output: Journal Publication › Article › peer-review

Open Access

34 Citations (Scopus)

Interaction of the maturation protein of the bacteriophage MS2 and the sex pilus of the Escherichia coli F plasmid

Spankie, T. J., Haywood, A. L., Dottorini, T., Barrow, P. A. & Hirst, J. D., Dec 2020, In: Journal of Molecular Graphics and Modelling. 101, 107723.

Research output: Journal Publication › Article › peer-review

Open Access

1 Citation (Scopus)

Thapsigargin at non-cytotoxic levels induces a potent host antiviral response that blocks influenza a virus replication

Goulding, L. V., Yang, J., Jiang, Z., Zhang, H., Lea, D., Emes, R. D., Dottorini, T., Pu, J., Liu, J. & Chang, K. C., Oct 2020, In: Viruses. 12, 10, 1093.

Research output: Journal Publication › Article › peer-review

Open Access

19 Citations (Scopus)

2019

Communication of prostate cancer cells with bone cells via extracellular vesicle RNA; a potential mechanism of metastasis

Probert, C., Dottorini, T., Speakman, A., Hunt, S., Nafee, T., Fazeli, A., Wood, S., Brown, J. E. & James, V., 7 Mar 2019, In: Oncogene. 38, 10, p. 1751-1763 13 p.

Research output: Journal Publication › Article › peer-review

Open Access

65 Citations (Scopus)

Developing and evaluating threshold-based algorithms to detect drinking behavior in dairy cows using reticulorumen temperature

Vázquez-Diosdado, J. A., Miguel-Pacheco, G. G., Plant, B., Dottorini, T., Green, M. & Kaler, J., Nov 2019, In: Journal of Dairy Science. 102, 11, p. 10471-10482 12 p.

Research output: Journal Publication › Article › peer-review

Open Access

12 Citations (Scopus)

Evolution of gene expression levels in the male reproductive organs of Anopheles mosquitoes

Izquierdo, A., Fahrenberger, M., Persampieri, T., Benedict, M. Q., Giles, T., Catteruccia, F., Emes, R. D. & Dottorini, T., 2019, In: Life Science Alliance. 2, 1, e201800191.

Research output: Journal Publication › Article › peer-review

Open Access

7 Citations (Scopus)

Re: Communication of Prostate Cancer Cells with Bone Cells via Extracellular Vesicle RNA; A Potential Mechanism of Metastasis

Probert, C., Dottorini, T., Speakman, A., Hunt, S., Nafee, T., Fazeli, A., Wood, S., Brown, J. E. & James, V., 1 Dec 2019, In: Journal of Urology. 202, 6, p. 1101 1 p.

Research output: Journal Publication › Comment/debate

Transcriptional plasticity buffers genetic variation in zinc homeostasis

Pita-Barbosa, A., Ricachenevsky, F. K., Wilson, M., Dottorini, T. & Salt, D. E., 1 Dec 2019, In: Scientific Reports. 9, 1, 19482.

Research output: Journal Publication › Article › peer-review

Open Access

24 Citations (Scopus)

2018

Acute toxoplasma gondii infection in cats induced tissue-specific transcriptional response dominated by immune signatures

Cong, W., Dottorini, T., Khan, F., Emes, R. D., Zhang, F. K., Zhou, C. X., He, J. J., Zhang, X. X., Elsheikha, H. M. & Zhu, X. Q., 19 Oct 2018, In: Frontiers in Immunology. 9, OCT, 2403.

Research output: Journal Publication › Article › peer-review

Open Access

12 Citations (Scopus)

A recombinant Fasciola gigantica 14-3-3 epsilon protein (rFg14-3-3e) modulates various functions of goat peripheral blood mononuclear cells

Tian, A. L., Lu, M., Calderón-Mantilla, G., Petsalaki, E., Dottorini, T., Tian, X., Wang, Y., Huang, S. Y., Hou, J. L., Li, X., Elsheikha, H. M. & Zhu, X. Q., 6 Mar 2018, In: Parasites and Vectors. 11, 1, 152.

Research output: Journal Publication › Article › peer-review

Open Access

28 Citations (Scopus)

Discrimination of contagious and environmental strains of Streptococcus uberis in dairy herds by means of mass spectrometry and machine-learning

Esener, N., Green, M. J., Emes, R. D., Jowett, B., Davies, P. L., Bradley, A. J. & Dottorini, T., 1 Dec 2018, In: Scientific Reports. 8, 1, 17517.

Research output: Journal Publication › Article › peer-review

Open Access

26 Citations (Scopus)

Evaluation of sampling frequency, window size and sensor position for classification of sheep behaviour

Walton, E., Casey, C., Mitsch, J., Vázquez-Diosdado, J. A., Yan, J., Dottorini, T., Ellis, K. A., Winterlich, A. & Kaler, J., Feb 2018, In: Royal Society Open Science. 5, 2, 171442.

Research output: Journal Publication › Article › peer-review

Open Access

76 Citations (Scopus)

Feature selection and comparison of machine learning algorithms in classification of grazing and rumination behaviour in sheep

Mansbridge, N., Mitsch, J., Bollard, N., Ellis, K., Miguel-Pacheco, G. G., Dottorini, T. & Kaler, J., 19 Oct 2018, In: Sensors. 18, 10, 3532.

Research output: Journal Publication › Article › peer-review

Open Access

93 Citations (Scopus)

2016

Radical remodeling of the Y chromosome in a recent radiation of malaria mosquitoes

Hall, A. B., Papathanos, P. A., Sharma, A., Cheng, C., Akbari, O. S., Assour, L., Bergman, N. H., Cagnetti, A., Crisanti, A., Dottorini, T., Fiorentini, E., Galizi, R., Hnath, J., Jiang, X., Koren, S., Nolan, T., Radune, D., Sharakhova, M. V., Steele, A. & Timoshevskiy, V. A. & 8 others, Windbichler, N., Zhang, S., Hahn, M. W., Phillippy, A. M., Emrich, S. J., Sharakhov, I. V., Tu, Z. J. & Besansky, N. J., 12 Apr 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 15, p. E2114-E2123

Research output: Journal Publication › Article › peer-review

Open Access

72 Citations (Scopus)

2015

Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes

Neafsey, D. E., Waterhouse, R. M., Abai, M. R., Aganezov, S. S., Alekseyev, M. A., Allen, J. E., Amon, J., Arcà, B., Arensburger, P., Artemov, G., Assour, L. A., Basseri, H., Berlin, A., Birren, B. W., Blandin, S. A., Brockman, A. I., Burkot, T. R., Burt, A., Chan, C. S. & Chauve, C. & 100 others, Chiu, J. C., Christensen, M., Costantini, C., Davidson, V. L. M., Deligianni, E., Dottorini, T., Dritsou, V., Gabriel, S. B., Guelbeogo, W. M., Hall, A. B., Han, M. V., Hlaing, T., Hughes, D. S. T., Jenkins, A. M., Jiang, X., Jungreis, I., Kakani, E. G., Kamali, M., Kemppainen, P., Kennedy, R. C., Kirmitzoglou, I. K., Koekemoer, L. L., Laban, N., Langridge, N., Lawniczak, M. K. N., Lirakis, M., Lobo, N. F., Lowy, E., MacCallum, R. M., Mao, C., Maslen, G., Mbogo, C., McCarthy, J., Michel, K., Mitchell, S. N., Moore, W., Murphy, K. A., Naumenko, A. N., Nolan, T., Novoa, E. M., O'Loughlin, S., Oringanje, C., Oshaghi, M. A., Pakpour, N., Papathanos, P. A., Peery, A. N., Povelones, M., Prakash, A., Price, D. P., Rajaraman, A., Reimer, L. J., Rinker, D. C., Rokas, A., Russell, T. L., Sagnon, N., Sharakhova, M. V., Shea, T., Simão, F. A., Simard, F., Slotman, M. A., Somboon, P., Stegniy, V., Struchiner, C. J., Thomas, G. W. C., Tojo, M., Topalis, P., Tubio, J. M. C., Unger, M. F., Vontas, J., Walton, C., Wilding, C. S., Willis, J. H., Wu, Y. C., Yan, G., Zdobnov, E. M., Zhou, X., Catteruccia, F., Christophides, G. K., Collins, F. H., Cornman, R. S., Crisanti, A., Donnelly, M. J., Emrich, S. J., Fontaine, M. C., Gelbart, W., Hahn, M. W., Hansen, I. A., Howell, P. I., Kafatos, F. C., Kellis, M., Lawson, D., Louis, C., Luckhart, S., Muskavitch, M. A. T., Ribeiro, J. M., Riehle, M. A., Sharakhov, I. V., Tu, Z., Zwiebel, L. J. & Besansky, N. J., 2 Jan 2015, In: Science. 347, 6217, 1258522.

Research output: Journal Publication › Article › peer-review

Open Access

410 Citations (Scopus)

VEGF and LPS synergistically silence inflammatory response to Plasmodium berghei infection and protect against cerebral malaria

Canavese, M., Dottorini, T. & Crisanti, A., Sept 2015, In: Pathogens and Global Health. 109, 6, p. 255-265 11 p.

Research output: Journal Publication › Article › peer-review

Open Access

10 Citations (Scopus)

2013

CluGene: A Bioinformatics Framework for the Identification of Co-Localized, Co-Expressed and Co-Regulated Genes Aimed at the Investigation of Transcriptional Regulatory Networks from High-Throughput Expression Data

Dottorini, T., Palladino, P., Senin, N., Persampieri, T., Spaccapelo, R. & Crisanti, A., 18 Jun 2013, In: PLoS ONE. 8, 6, e66196.

Research output: Journal Publication › Article › peer-review

Open Access

8 Citations (Scopus)

Regulation of Anopheles gambiae male accessory gland genes influences postmating response in female

Dottorini, T., Persampieri, T., Palladino, P., Baker, D. A., Spaccapelo, R., Senin, N. & Crisanti, A., Jan 2013, In: FASEB Journal. 27, 1, p. 86-97 12 p.

Research output: Journal Publication › Article › peer-review

Open Access

14 Citations (Scopus)

2012

Roles of the amino terminal region and repeat region of the plasmodium berghei circumsporozoite protein in parasite infectivity

Aldrich, C., Magini, A., Emiliani, C., Dottorini, T., Bistoni, F., Crisanti, A. & Spaccapelo, R., 29 Feb 2012, In: PLoS ONE. 7, 2, e32524.

Research output: Journal Publication › Article › peer-review

Open Access

34 Citations (Scopus)

Silencing of the Hsf gene, the transcriptional regulator of A. Gambiae male accessory glands, inhibits the formation of the mating plug in mated females and disrupts their monogamous behaviour

Dottorini, T., Persampieri, T., Palladino, P., Spaccapelo, R. & Crisanti, A., Nov 2012, In: Pathogens and Global Health. 106, 7, p. 405-412 8 p.

Research output: Journal Publication › Article › peer-review

Open Access

11 Citations (Scopus)

2011

Disruption of plasmepsin-4 and merozoites surface protein-7 genes in Plasmodium berghei induces combined virulence-attenuated phenotype

Spaccapelo, R., Aime, E., Caterbi, S., Arcidiacono, P., Capuccini, B., Di Cristina, M., Dottorini, T., Rende, M., Bistoni, F. & Crisanti, A., 2011, In: Scientific Reports. 1, 39.

Research output: Journal Publication › Article › peer-review

Open Access

22 Citations (Scopus)

Gepoclu: A software tool for identifying and analyzing gene positional clusters in large-scale gene expression analysis

Dottorini, T., Senin, N., Mazzoleni, G., Magnusson, K. & Crisanti, A., 26 Jan 2011, In: BMC Bioinformatics. 12, 34.

Research output: Journal Publication › Article › peer-review

Open Access

4 Citations (Scopus)

Serum igE reactivity profiling in an Asthma affected Cohort

Dottorini, T., Sole, G., Nunziangeli, L., Baldracchini, F., Senin, N., Mazzoleni, G., Proietti, C., Balaci, L. & Crisanti, A., 2011, In: PLoS ONE. 6, 8, e22319.

Research output: Journal Publication › Article › peer-review

Open Access

12 Citations (Scopus)

Transcription regulation of sex-biased genes during ontogeny in the Malaria vector Anopheles gambiae

Magnusson, K., Mendes, A. M., Windbichler, N., Papathanos, P. A., Nolan, T., Dottorini, T., Rizzi, E., Christophides, G. K. & Crisanti, A., 2011, In: PLoS ONE. 6, 6, e21572.

Research output: Journal Publication › Article › peer-review

Open Access

67 Citations (Scopus)

2010

Plasmepsin 4-deficient Plasmodium berghei are virulence attenuated and induce protective immunity against experimental malaria

Spaccapelo, R., Janse, C. J., Caterbi, S., Franke-Fayard, B., Bonilla, J. A., Syphard, L. M., Di Cristina, M., Dottorini, T., Savarino, A., Cassone, A., Bistoni, F., Waters, A. P., Dame, J. B. & Crisanti, A., Jan 2010, In: American Journal of Pathology. 176, 1, p. 205-217 13 p.

Research output: Journal Publication › Article › peer-review

Open Access