Biocompatibility of Biomaterials for Tissue Regeneration or Replacement

Emerging biomaterials for tissue engineering applications witness a multitude of interaction (both along their interface and internally) with human tissue. Insufficient consideration of the spatial and temporal aspects of these biomaterial-tissue interactions often raise biocompatibility concerns. This review focuses on strategies implemented in some of the recently developed biomaterials—particularly for soft and hard tissue regeneration or replacement—to overcome potential foreign body response and ensure effective functioning of the biomaterial.