Malaysia’s breakthrough in modern actinobacteria (Mod-actino) drug discovery research

Angel Yun Kuan Thye, Vengadesh Letchumanan, Loh Teng Hern Tan, Jodi Woan Fei Law, Learn Han Lee

Research output: Journal PublicationReview articlepeer-review

15 Citations (Scopus)

Abstract

Actinobacteria are well-known producers of metabolites with medicinal value. The application of actinobacterial compounds has been expanded to other fields, including agriculture, aquaculture, and cosmeceutical. With this, the term “Modern Actinobacteria” (MOD-ACTINO) was first coined by a Malaysian researcher, Associate Professor Dr. Lee Learn Han, to define actinobacteria with modern applications. The present review aims to highlight the MOD-ACTINO research achievements in Malaysia. The Malaysian MOD-ACTINO strains are capable of exerting a wide range of bioactivities such as antimicrobial/anti-MRSA, anticancer, antioxidant, antifungal, and antimalarial. Research on MOD-ACTINO is highly encouraged to harness the benefits of actinobacteria and unravel important metabolites for various applications.

Original languageEnglish
Article numbera0000275
JournalProgress in Microbes and Molecular Biology
Volume5
Issue number1
DOIs
Publication statusPublished - 20 Jan 2022
Externally publishedYes

Keywords

  • Actinomycetes
  • Anticancer
  • Antimicrobial
  • Antioxidant
  • Drug discovery
  • Modern actinobacteria
  • Streptomycetes

ASJC Scopus subject areas

  • Molecular Biology
  • Microbiology (medical)
  • Microbiology
  • Biochemistry, Genetics and Molecular Biology (miscellaneous)

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