Multigram Synthesis of Trioxanes Enabled by a Supercritical CO₂Integrated Flow Process

Keyphrases

• 1,2,4-trioxanes 66%
• Antimalarial Activity 33%
• Continuous Approach 33%
• Continuous Processing 33%
• Gram-scale 33%
• High Atom Utilization 33%
• Molecular Oxygen 33%
• Multigram Synthesis 100%
• Multigrams 33%
• Para-substituted Phenols 33%
• Solid Oxidizer 33%
• Synthetic Organic Chemistry 33%
• Value-added Compounds 33%

Chemistry

• Dioxygen 20%