Synthesis of aziridines with multiple chiral substitutions by copper-catalyzed diastereoselective radical aminotrifluoromethylation of alkenes

Keyphrases

• Alkenes 100%
• Aminotrifluoromethylation 100%
• Aziridine 100%
• Chemical Yield 33%
• Chiral Directing Groups 33%
• Chiral Sulfinyl Imines 33%
• Copper-catalyzed 100%
• DFT Calculations 33%
• Diastereoselective 100%
• Diastereoselectivity 33%
• Drug Molecules 33%
• Functional Group Tolerance 33%
• Nucleophile 33%
• Proline 33%
• Rapid Synthesis 33%
• Reaction Mechanism 33%
• Synthetic Strategies 33%

Chemistry

• Alkene 100%
• Aziridine 100%
• Density Functional Theory 33%
• Diastereoselectivity 33%
• Nucleophile 33%
• Proline 33%
• Reaction Yield 33%